ResonantAcoustic® Mixing (RAM) Technology and Mechanochemistry Working Hand in Hand

Mechanochemistry is a field of chemistry that focuses on chemical reactions induced by mechanical forces such as grinding, shearing, milling, or mixing. Mechanochemistry reduces, or even eliminates, the use of solvents, heat, electricity, and other external elements to reactions. Reactions requiring multiple intermediary products may also be simplified.

Traditional processing/mixing methodologies varied from hand grinding (i.e., mortar and pestle) to shaker and planetary mills for laboratory scale production.

Eccentric and horizontal high-energy ball mill devices had been the preferred methodology for scale up to batch production. Twin-screw and single-screw extrusion equipment were previously advantageous for continuous mechanochemical processing.

Illustrating clear advantages (massively reduced process times and increased conversion) to the aforementioned traditional processes, ResonantAcoustic® Mixing leverages low frequency acoustic waves to generate controlled mechanical force within a reaction vessel.

The short video below describes some distinct advantages of ResonantAcoustic® Mixing over legacy technologies:

TESTIMONIAL: Dr. Friščić at his Technical InterChange keynote speech announced that his team and the team at Genentech received the 2024 American Chemical Society Award for Affordable Green Chemistry!

Dr. Friščić is currently a Professor and Leverhulme International Chair in Green and Sustainable Chemistry at the University of Birmingham (U.K.). With his group and collaborators, he has co-authored >300 publications, book chapters and patent applications, and has received a multitude of international awards.

The energy produced through ResonantAcoustic® Mixing disrupts chemical bonds and increases the chance of collision between particles promoting reaction kinetics.

Both acceleration and frequency are precisely controlled elements of ResonantAcoustic® Mixing technology, allowing chemists to tailor the reaction conditions and selectivity.

Temperature control and vacuum options are also available. The ability to fine-tune the reaction environment is invaluable toward specific product outcomes in mechanochemistry.

System and process scale up has been identified as a pressing challenge toward the further advancement of mechanochemistry production. ResonantAcoustic® Mixing provides a consistent platform for both batch and continuous mechanochemical processing scale-up.

To learn more about industrial mixing with RAM technology and mechanochemistry download the informative folio:  https://resodynmixers.com/download/mechanochemistry-folio/