RAM5 Pharma
Production Mixer - Continuous
Resodyn Acoustic Mixers' production scale pharmaceutical mixer, the RAM5 Pharma Continuous, brings the awesome power of ResonantAcoustic® Mixing to larger scale to drastically increase productivity and expand capabilities. Built on flexible and universal processing capabilities, the RAM5 Pharma delivers exceptional RSD (Relative Standard Deviation) results, improved efficiency with rapid mixing and dispersion times, and new product opportunities at a larger payload capacity for RAM batch and continuous systems. Each RAM5 Pharma configuration matches the right processing functions with critical processing demands and exceeds the required performance beyond traditional technologies.
Need a custom solution? All mixers can be customized for unique automations and applications.
Pharmaceutical-Grade Performance at Production Scale
The RAM 5 Pharma is purpose-built for pharmaceutical manufacturers who have outgrown bench-scale development and need the same mixing quality, content uniformity, and process reproducibility they saw in R&D. Since the RAM process is consistent across scales, the transition from R&D to production is seamless, unlike conventional mixing equipment.
The RAM5 Pharma mixer creates enormous quantities of products. The flexibility of vessel size and shape allows for a rapid change in inputs and outputs. The enclosed structure allows for easy cleaning and sanitization.
Key Processing Capabilities
- Processes up to 80 lb (36 kg) per batch
- Handles solids, powders, liquids, gases, and viscous materials
- Supports milling, grinding, sieving, and coating (spray or dry)
- Enables temperature control
- Offers vacuum processing
- Provides real-time monitoring and downloadable data for analysis
- Stores up to 100 recipes for repeatable operations
Key Advantages
- 10–100x faster processing compared to traditional mixers
- Highly repeatable results for consistent product quality
- Direct scalability across the RAM product line
- Exceptional ingredient distribution
- Proven performance across global industries and applications
- Variety of certifications available
GMP and Contamination Free
RAM uses vibrational energy instead of impellers or blades, and mixing occurs in sealed containers, minimizing cross-contamination, exposure risks, and reducing cleaning validation burdens — all crucial for GMP compliance. This bladeless, closed-system approach is not simply a convenience — for pharmaceutical manufacturers, it is a critical compliance and safety advantage that streamlines regulatory approval and reduces the time and cost associated with cleaning validation between product runs.
RAM ensures uniform distribution of active pharmaceutical ingredients (APIs) even at low concentrations — such as below 1% — which helps maintain dose accuracy and content uniformity, critical for tablet and capsule formulations.
Comprehensive Processing Capabilities
Key processing capabilities include mixing and processing 80 lbs (36 kg) or more of any combination of solids and powders from nano-scale up, liquids and gases, and viscous and slurry materials, as well as coating, milling, and grinding processes, all with onboard control of processing accessories.
The RAM5 Pharma is available with a full menu of processing options including temperature monitoring and control and mixing under vacuum. Standard functions include recipe development and retention, real-time parameter monitoring and recording, 100% processing data retention, multiple operator security levels, and multiple mixing vessel options. The system supports up to 80 lbs of mix capacity in extendable 5-gallon mixing vessels with application-specific vessel options.
Proven in the World's Top Pharmaceutical Operations
From the world's top pharmaceutical companies to international manufacturers and global tech giants, Resodyn Acoustic Mixer installations in over 40 countries are in use today, all sharing a single, powerful technology platform. The RAM5 Pharma represents that platform at its most powerful production-ready pharmaceutical configuration — delivering the speed, uniformity, and traceability demanded by modern drug manufacturing.
Real-world impact is well documented. One pharmaceutical manufacturer reported challenges mixing a viscous, 10,000 cP solids-loaded transdermal cream consisting of water, excipient, API, and a sticky acrylate adhesive — a process that previously required multiple material addition steps and up to eight hours with an overhead stirrer. With a Resodyn RAM system, that mix was completed in just over two minutes.
Compare the RAM family
ResonantAcoustic® mixing scaled to your needs, from the lab to the production floor.
